Journal of Cerebrovascular Disease 2020 Vol.3 No.3 15-26

Research Progress of Chronic Internal Carotid Artery Occlusion

Author(s): Dong-Hai Wang1,Zhen-Qiang Li2,Cheng-Feng Sun2,Bo-Ding Wang2

Affiliation(s): 1College of Medicine, Ningbo University, Ningbo 315000, China
2Department of Neurosurgery, Ningbo Medical Center Lihuili Eastern Hospital, Ningbo 315000, China

Corresponding Author: Bo-Ding Wang

Corresponding email(s):

Key Words: Ischemic stroke; Chronic internal carotid artery occlusion; Carotid endarterectomy; Endovascular therapy


Chronic internal carotid artery occlusion (CICAO) is a chronic cerebrovascular disease which, from various causes, leads to progressive stenosis of the internal carotid artery lumen and finally to complete occlusion. With an aging society, the detection rate of CICAO is increasing year by year, with the highest incidence of CICAO in elderly men. The main clinical manifestations of CICAO are ischemic stroke and transient ischemic attack. Drug therapy is the first choice for asymptomatic CICAO, and surgical treatment is an optional means of improving prognosis for symptomatic CICAO that cannot be controlled by drugs. The selection of indications needs further study. This article reviews the latest research progress in the epidemiology, etiology, clinical features, imaging analysis, and treatment of CICAO in order to guide clinical diagnosis and treatment.

Full Text: 

On-line Access: 2020-09-01

Received: 2020-07-11

Revision Accepted: 2020-08-18

Publish: 2020-09-01

Clicked: 831